Stem Cells in Gastrointestinal Cancers
نویسندگان
چکیده
Aiwu Ruth Hea,∗, Jonathan Mendelsonb, Tiffany Blakeb, Lopa Mishrab,c and John L. Marshalla Division of Hematology/Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, USA Laboratory of Cancer Genetics, Digestive Diseases, and Developmental Molecular Biology, Department of Surgery, Lombardi Cancer Center, Georgetown University, Washington, DC, USA Laboratory of Digestive Diseases, Department of Surgery, DVAMC, Washington, DC, USA
منابع مشابه
What are Stem Cells?
Stem cells are undifferentiated self regenerating multi potential cells. There are three types of stem cells categories by the ability to form after cells and correlated with the body’s development process. Totipotent: these stem cells can form an entire organism such as fertilized egg. Ploripotent: ploripotent cells are those that can form any cell in the body but cannot form an entire organ...
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Cancer stem cells (CSCs) have been identified as rare cellular populations in many cancers, including leukemia and solid tumors. This minor subpopulation of cancerous cells is immortal tumor-initiating cells which thought to be responsible for cancer initiation, progression, metastasis, recurrence and drug/radiation resistance. Low proliferative rate, high self-renewing capacity, differentiatio...
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BACKGROUND:Canine mammary gland cancers are the most prevalent malignancies in dogs. There are different challenges regarding management of these cancers in dogs and human, one hypothesis is related to small cellular subset of tumor mass called cancer stem cell. These cells are therapy resistant and cause metastasis and relapse even after primary successful treatment. The well-identified phenot...
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Stem cells occur in many somatic tissues of multicellular organism and are important participants in their physiology. Stem cells have three distinctive properties: 1- self-renewal, 2- the potential to proliferate extensively and 3- capability to develop into multiple lineages. Every time a stem cell divides, it makes one exact copy and one progenitor cell. Progenitor cells have finite division...
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Background and purpose: Angiogenesis provides proper nutrition and helps to the development and spread of cancer cells. Cancer stem cells are a rare population of tumor cells responsible for initiation, spreading and growth of cancer. Angiogenesis occurs more in cancer stem cells compared with other cancer cells. Ibuprofen, as a member of nonsteroidal anti-inflammatory drugs (NSAIDs) group is u...
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عنوان ژورنال:
دوره 24 شماره
صفحات -
تاریخ انتشار 2008